She appeared in several television series and commercials, before acquiring her first significant role prior to her 15th birthday, playing Jackie Burkhart on the television series That '70s Show (1998–2006).
The film was directed and co-written by Family Guy creator Seth Mac Farlane.
Director John Moore defended his choice of Kunis saying, "Mila just bowled us over.....
She wasn't an obvious choice, but she just wears Mona so well.
Her other major films include the neo-noir action film Max Payne (2008), the post-apocalyptic action film The Book of Eli (2010), the romantic comedy film Friends with Benefits (2011), the comedy film Ted (2012), the fantasy film Oz the Great and Powerful (2013) as the Wicked Witch of the West, and the comedy film Bad Moms (2016). All who auditioned were required to be at least 18 years old; Kunis, who was 14 at the time, told the casting directors she would be 18 but did not say when.
She stated in 2011 that her parents had "amazing jobs", and that she "was very lucky" and the family was "not poor"; they had decided to leave the USSR because they saw "no future" there for Mila and her brother. Though they eventually figured it out, the producers still thought Kunis was the best fit for the role.
Judge said: "As beautiful as Mila is, you could believe that maybe she would cross paths with you in the real world." After seeing Kunis perform in Forgetting Sarah Marshall, Judge wanted to cast her in the role of Cindy in Extract: "I just thought, 'Wow, this girl's perfect.' And she really wanted to do it, which was fantastic." Kunis herself stated that "I'm a huge fan of Mike Judge's from Office Space, so I was, like, 'Okay, this is a very easy decision.' I told them I would do anything needed to be in this production– like craft service, or, say, acting." Even reviewers who didn't necessarily like the film complimented her performance, such as James Berardinelli, who wrote that "the demands of the role prove to be within her range, which is perhaps surprising considering she has been thus far pigeonholed into more lightweight parts", and Colin Covert of the Star Tribune, who wrote that she "generated a spark and brought a degree of determination to her character, developing an independent female character who's not always in need of rescuing." Kunis was nominated for multiple awards, including her first Golden Globe, for the 2010 film Black Swan.